How and where to order Gabapentin (Neurontin) 100 mg, 300 mg, 400 mg, 600 mg, 800 mg capsules or tablets online on the Neurointerventions website:
Indications and usage:
Neurontin (Gabapentin) is indicated for:
Dosage and administration:
Epilepsy with partial onset seizures
Gabapentin dose should be adjusted in patients with reduced renal function.
Dosage forms and strengths:
Signs of acute toxicity in animals included ataxia, labored breathing, ptosis, sedation, hypoactivity, or excitation.
Acute oral overdoses of gabapentin have been reported. Symptoms have included double vision, tremor, slurred speech, drowsiness, altered mental status, dizziness, lethargy, and diarrhea. Fatal respiratory depression has been reported with Neurontin overdose, alone and in combination with other CNS depressants.
Gabapentin can be removed by hemodialysis.
Known hypersensitivity to gabapentin or ingredients of its pharmaceutical forms.
Warnings and precautions:
Side effects, adverse reactions:
Most common adverse reactions of gabapentin (incidence >= 8% and at least twice that for placebo) were:
To report suspected adverse reactions, contact Pfizer Inc. or your local FDA.
Concentrations increased by morphine; may need dose adjustment.
Armodafinil (Nuvigil, Waklert)
Use in specific populations:
Based on animal data, may cause fetal harm.
Patient counseling information:
Inform patients that Neurontin (Gabapentin) is taken orally with or without food. Inform patients that, should they divide the scored 600 mg or 800 mg tablet in order to administer a half-tablet, they should take the unused half-tablet as the next dose. Advise patients to discard half-tablets not used within 28 days of dividing the scored tablet.
Drug reaction with eosinophilia and systemic symptoms (DRESS)/multiorgan hypersensitivity
Prior to initiation of treatment with gabapentin, instruct patients that a rash or other signs or symptoms of hypersensitivity (such as fever or lymphadenopathy) may herald a serious medical event and that the patient should report any such occurrence to a physician immediately.
Anaphylaxis and angioedema
Advise patients to discontinue Neurontin and seek medical care if they develop signs or symptoms of anaphylaxis or angioedema.
Dizziness and somnolence and effects on driving and operating heavy machinery
Advise patients that Gabapentin (Neurontin) may cause dizziness, somnolence, and other symptoms and signs of CNS depression. Other drugs with sedative properties may increase these symptoms. Accordingly, although patients' ability to determine their level of impairment can be unreliable, advise them neither to drive a car nor to operate other complex machinery until they have gained sufficient experience on Neurontin to gauge whether or not it affects their mental and/or motor performance adversely. Inform patients that it is not known how long this effect lasts.
Suicidal thinking and behavior
Counsel the patient, their caregivers, and families that AEDs, including gabapentin, may increase the risk of suicidal thoughts and behavior. Advise patients of the need to be alert for the emergence or worsening of symptoms of depression, any unusual changes in mood or behavior, or the emergence of suicidal thoughts, behavior, or thoughts about self-harm. Instruct patients to report behaviors of concern immediately to healthcare providers.
Inform patients about the risk of respiratory depression. Include information that the risk is greatest for those using concomitant CNS depressants (such as opioid analgesics) or those with underlying respiratory impairment. Teach patients how to recognize respiratory depression and advise them to seek medical attention immediately if it occurs.
Use in pregnancy
Instruct patients to notify their physician if they become pregnant or intend to become pregnant during therapy, and to notify their physician if they are breast feeding or intend to breast feed during therapy.
Encourage patients to enroll in the NAAED Pregnancy Registry if they become pregnant. This registry is collecting information about the safety of antiepileptic drugs during pregnancy.
Here is a list of popular medications containing gabapentin as a main active pharmaceutical ingredient; their trade names, forms, doses, companies - manufacturers, distributors, suppliers, researchers and developers: